antiplatelet aggregation plants

  • Evaluation of Anti-Platelet Aggregation Effect of Some ...

    Anti-platelet aggregation activity is not uncommon from plants extracts. Gady’s et al (2009) have reported a significant platelet aggregation inhibitory activity from the total aqueous extract of leaves of parsley (IC 50: 5.6mg/ml) against the aggregation induced by ADP .

    Cited by: 7
  • Plant Alkaloids as Antiplatelet Agent: Drugs of the Future ...

    Antiplatelet mechanism of plant alkaloids. Various mechanisms have been proposed for the antiplatelet activity of different isolated plant-alkaloids (Figure (Figure1). 1).Researchers have proposed that berberine significantly inhibited platelet aggregation by inhibiting synthesis of thromboxane A2 induced by adenine diphosphate, arachidonic acid, collagen (Chu et al., 1996).

    Cited by: 5
  • antiplatelet aggregation plants-[mining plant]

    Antiplatelet activity of white and pink Nelumbo nucifera Gaertn .... antiplatelet aggregation property, different concentrations (100, 200, 300, 400 and 500µg/ml) of plant extract were added to the platelet suspension for 1min exposure

  • Plant Alkaloids as Antiplatelet Agent: Drugs of the Future ...

    Sep 22, 2016  The commonly used antiplatelet, aspirin, originated from salicin obtained from willow plant commonly used in pain medication. This review describes various alkaloids isolated from plant sources having antiplatelet activity with possible mechanisms and candidates for further detailed studies in the drug discovery as antiplatelet agents.

    Cited by: 5
  • Antiplatelet aggregation activity of diterpene alkaloids ...

    Aug 02, 2002  japonica var. incisa, was found to selectively inhibit rabbit platelet aggregation induced by arachidonic acid in vitro and ex vivo and that the inhibition was much stronger than that of aspirin (Shen et al., 2000). In the present study, the antiplatelet aggregation activities of some natural atisine-type alkaloids isolated from S.

    Cited by: 26
  • Evaluation of Anti-Platelet Aggregation Effect of Some ...

    Evaluation of Anti-Platelet Aggregation Effect of Some Allium Species Zahra Lorigooini a , Seyed Abdolmajid Ayatollahi a,b , Salimeh Amidi a and Farzad Kobarfard a,b*

  • Antiplatelet drugs - list of drugs, indications, side ...

    History. Antiplatelet drugs are widely used to prevent arterial thrombosis in various cardiovascular-related conditions. Acetylsalicylic acid (aspirin), is a famous drug used since ancient times, and even then it was known that plants which contain salicylate such as willow can reduce the pain and fever.In 1897, a German scientist Felix Hoffman who was working for Bayer has synthesized aspirin.

  • Comparative study of Antiplatelet Aggregation Activity of ...

    Plant extracts having an antiplatelet aggregation activity may be a potential choice for development of anti-inflammatory drugs because of their natural origin. The extraction of bioactive compounds being the most crucial step in the commercial development of natural products it is essential to have rapid and efficient phytochemical

  • antiplatelet aggregation plants - greenrevolution.org

    Antiplatelet Aggregation Coumarins from the Leaves of Murraya omphalocarpa204 Кб. Both compounds 1 and 2 are active in the antiplatelet aggregation assay.Plant Material Fresh leaves of M. omphalocarpa were collected from Pingtung County, Taiwan, in September 1999, and...

  • Medicinal Herbals with Antiplatelet Properties Benefit in ...

    Medicinal plants serve as a greater resource for new medication and their potential currently became a topic of interest to the researchers all over the world. Traditionally, certain herbs have been used as a treatment for heart diseases but have been investigated for their antiplatelet properties.

  • List of Platelet aggregation inhibitors - Drugs

    Platelet aggregation inhibitors work in different places of the clotting cascade and prevent platelet adhesion, therefore no clot formation. Aspirin, the most commonly used antiplatelet drug changes the balance between prostacyclin (which inhibits platelet aggregation) and thromboxane (that promotes aggregation).

  • Antiplatelet Aggregation Activity of Walnut Hull Extract ...

    In this equation, APA is the percentage of antiplatelet aggregation, A T is the absorbance at the end of reaction for the test sample (extract- and thrombin-treated cells), and A C is the absorbance at the end of reaction for control sample (thrombin-treated cells). 2.11.

  • Antiplatelet Aggregation Coumarins from the Leaves of ...

    Antiplatelet Aggregation Coumarins from the Leaves of Murraya omphalocarpa Yi-Chen Chia 1, Fang-Rong Chang 2, Jinn-Chyi Wang 1, Chin-Chung Wu 2, Michael Y.-N. Chiang 3, Yu-Hsuan Lan 2, Keh-Shaw Chen 1,* and Yang-Chang Wu 2,* 1 Department of Food Science and Technology, Ta-Jen University, Ping Tung Hsien, Taiwan

    Published in: Molecules 2008Authors: Yi Chen Chia Fang Rong Chang Jinn Chyi Wang Chin Chung Wu Michael Y N CAffiliation: Kaohsiung Medical University National Sun Yat Sen UniversityAbout: X-ray Platelet-activating factor Coumarin
  • Cytotoxic and Antiplatelet Aggregation Principles of Ruta ...

    The structural elucidation of these isolated compounds were determined by the spectroscopic methods and/or comparison of the physical data with literature values. Their antiplatelet aggregation and cytotoxic activities were examined to find potent antiplatelet aggregation and cytotoxic compounds from natural resources.

  • Plant Alkaloids as Antiplatelet Agent: Drugs of the Future ...

    Plant Alkaloids as Antiplatelet Agent: Drugs of the Future in the Light of Recent Developments Article (PDF Available) in Frontiers in Pharmacology 7(28) September 2016 with 271 Reads

  • Antiplatelet, Antithrombotic, and Fibrinolytic Activities ...

    In a previous work based on popular belief, Campomanesia xanthocarpa Berg., popularly known as “guavirova”, showed to have a potential effect in the control of a number of conditions associated with cardiovascular diseases. The aim of the present work was to investigate the effects of C. xanthocarpa extract (CXE) on antiplatelet, antithrombotic and fibrinolytic activities in mice and in ...

  • Antiplatelet, anticoagulant, and profibrinolytic ...

    Abstract. Baicalin is a flavonoid compound purified from the medicinal plant Scutellaria baicalensis Georgi and has been reported to possess anti-inflammatory and anti-viral activities. However, antiplatelet, anticoagulant, and profibrinolytic properties of baicalin have not been studied.

  • Evaluation of selected South African plant species for ...

    Evaluation of selected South African plant species for antioxidant, antiplatelet, and cytotoxic activity M. M. Suleiman1,2, V. Bagla1, ... was used to determine the inhibitory effect of the plant extracts on platelet aggregation. Briefly, fresh equine (Equus caballus) ...

  • (PDF) Antiplatelet actions of aporphinoids from formosan ...

    Antiplatelet actions of aporphinoids from formosan plants. Bioorganic Medicinal Chemistry Letters, 1999. Che-ming Teng. Yi-chen Chia. Keh-shaw Chen. Ya-ling Chang. Che-ming Teng. Yi-chen Chia. Keh-shaw Chen. Ya-ling Chang. Download with Google Download with Facebook

  • An Overview of Medicinal Plants as Potential Anti-Platelet ...

    An Overview of Medicinal Plants as Potential Anti-Platelet Agents Mridul Bhowal1, Darshika M Mehta2 1B Pharm, PES College of Pharmacy, 50 feet road, Hanumanthanagar, ... Chang FR, Wei JL, Teng CM, and Wu YC, Antiplatelet aggregation constituents from Annona purpurea, J

  • Cytotoxic and Antiplatelet Aggregation Principles of Ruta ...

    The structural elucidation of these isolated compounds were determined by the spectroscopic methods and/or comparison of the physical data with literature values. Their antiplatelet aggregation and cytotoxic activities were examined to find potent antiplatelet aggregation and cytotoxic compounds from natural resources.

  • Medicinal Herbals with Antiplatelet Properties Benefit in ...

    Medicinal plants serve as a greater resource for new medication and their potential currently became a topic of interest to the researchers all over the world. Traditionally, certain herbs have been used as a treatment for heart diseases but have been investigated for their antiplatelet properties.

  • Evaluation of selected South African plant species for ...

    Evaluation of selected South African plant species for antioxidant, antiplatelet, and cytotoxic activity M. M. Suleiman1,2, V. Bagla1, ... was used to determine the inhibitory effect of the plant extracts on platelet aggregation. Briefly, fresh equine (Equus caballus) ...

  • (PDF) Antiplatelet actions of aporphinoids from formosan ...

    Antiplatelet actions of aporphinoids from formosan plants. Bioorganic Medicinal Chemistry Letters, 1999. Che-ming Teng. Yi-chen Chia. Keh-shaw Chen. Ya-ling Chang. Che-ming Teng. Yi-chen Chia. Keh-shaw Chen. Ya-ling Chang. Download with Google Download with Facebook

  • An Overview of Medicinal Plants as Potential Anti-Platelet ...

    An Overview of Medicinal Plants as Potential Anti-Platelet Agents Mridul Bhowal1, Darshika M Mehta2 1B Pharm, PES College of Pharmacy, 50 feet road, Hanumanthanagar, ... Chang FR, Wei JL, Teng CM, and Wu YC, Antiplatelet aggregation constituents from Annona purpurea, J

  • Journal of Herbs, Spices Medicinal Plants - tandfonline

    In the antiplatelet aggregation inhibitory activity, the oil displayed action against the induced platelet aggregation in the order collagen (IC 50 < 1) > thrombin (IC 50 1.18) > Adenosine diphosphate (IC 50 2.32) > epinephrine (IC 50 3.65). The lethal concentration (LC 50)

  • Plant Alkaloids as Antiplatelet Agent: Drugs of the Future ...

    The commonly used antiplatelet, aspirin, originated from salicin obtained from willow plant commonly used in pain medication. This review describes various alkaloids isolated from plant sources having antiplatelet activity with possible mechanisms and candidates for further detailed studies in the drug discovery as antiplatelet agents.

  • PlantAlkaloidsasAntiplateletAgent ...

    plant species consist of alkaloids (Amirkia and Heinrich, 2014; Khan, 2016a). Alkaloids are mainly involved in the plant defense ... nymphaefolia possessed strong antiplatelet aggregation in vitro due to the presence of six alkaloids: laurotetanine, oxohernagine, thallicarpine,reticulline, vateamine, and hernandaline. The most

  • Antiplatelet activity of white and pink Nelumbo nucifera ...

    Antiplatelet activity of white and pink Nelumbo nucifera Gaertn flowers 581 CaCl2 at a final concentration of 2μM. Platelet aggregation was recorded by increasing transmittance value of spec-trophotometric measurements. To determine the in vitro antiplatelet aggregation property,

    Published in: Brazilian Journal of Pharmaceutical Sciences 2010Authors: Brindha Durairaj Arthi DoraiAffiliation: Psg College of Arts and ScienceAbout: Platelet Aspirin Chemical composition Platelet aggregation inhibitor Lotus Phar
  • In Vitro Platelet Aggregation Inhibition Activity of ...

    the percent antiplatelet activity with the succeeding formula: % Inhibition of Platelet Aggregation = The percent inhibition of platelet aggregation values compares the absorbance readings among treated (with plant extract or aspirin) controls and the untreated control. Percent Antiplatelet Activity

  • Medicinal Plants with Antiplatelet Activity - El Haouari ...

    The identification and/or structure modification of the plant constituents and the understanding of their action mechanisms will be helpful in the development of new antiplatelet agents based on medicinal plants which could contribute to the prevention of thromboembolic‐related disorders by inhibiting platelet aggregation.

  • Handbook of Compounds with Anti-Inflammatory and Anti ...

    This book presents 848 compounds isolated and identified from plants that present anti-inflammatory and antiplatelet aggregation activities. These substances have been classified by chemical groups and each provides the most relevant information of its pharmacological activity, action mechanism, chemical structure, spectroscopic date, and other properties.

    Author: Rosa Martha Perez Gutierrez
  • Antiplatelet Aggregation Coumarins from the Leaves of ...

    Using a bioactivity-guided fractionation method, two coumarins: minumicrolineacetonide (1) and epimurpaniculol senecioate (2), were isolated from the leaves ofMurraya omphalocarpa Hayata (Rutaceae). Compound 1 had been previously synthesizedand was now isolated from natural sources for the first time, and compound 2, possessing anegative optical rotation value, is new.

  • Cujete, Crescentia cujete, Calabash tree: Philippine ...

    • Antiplatelet Aggregation Activity /Flavonoid / Fruit: Study investigated C. cujete fruit for flavonoid content and platelet aggregation activity. Results showed potent antiplatelet aggregation activity which was attributed to flavonoid content. Acute oral toxicity categorized it as non-toxic based on OECD guidelines-423. (32)

  • Handbook of Compounds with Anti-Inflammatory and Anti ...

    This book presents 848 compounds isolated and identified from plants that present anti-inflammatory and antiplatelet aggregation activities. These substances have been classified by chemical groups and each provides the most relevant information of its pharmacological activity, action mechanism, chemical structure, spectroscopic date, and other properties.

    Author: Rosa Martha Perez Gutierrez
  • Antiplatelet activity of white and pink Nelumbo nucifera ...

    Antiplatelet activity of white and pink Nelumbo nucifera Gaertn flowers 581 CaCl2 at a final concentration of 2μM. Platelet aggregation was recorded by increasing transmittance value of spec-trophotometric measurements. To determine the in vitro antiplatelet aggregation property,

    Published in: Brazilian Journal of Pharmaceutical Sciences 2010Authors: Brindha Durairaj Arthi DoraiAffiliation: Psg College of Arts and ScienceAbout: Platelet Aspirin Chemical composition Platelet aggregation inhibitor Lotus Phar
  • Medicinal Plants with Antiplatelet Activity - El Haouari ...

    The identification and/or structure modification of the plant constituents and the understanding of their action mechanisms will be helpful in the development of new antiplatelet agents based on medicinal plants which could contribute to the prevention of thromboembolic‐related disorders by inhibiting platelet aggregation.

  • Antiplatelet Aggregation Coumarins from the Leaves of ...

    Using a bioactivity-guided fractionation method, two coumarins: minumicrolineacetonide (1) and epimurpaniculol senecioate (2), were isolated from the leaves ofMurraya omphalocarpa Hayata (Rutaceae). Compound 1 had been previously synthesizedand was now isolated from natural sources for the first time, and compound 2, possessing anegative optical rotation value, is new.

  • Cujete, Crescentia cujete, Calabash tree: Philippine ...

    • Antiplatelet Aggregation Activity /Flavonoid / Fruit: Study investigated C. cujete fruit for flavonoid content and platelet aggregation activity. Results showed potent antiplatelet aggregation activity which was attributed to flavonoid content. Acute oral toxicity categorized it as non-toxic based on OECD guidelines-423. (32)

  • Bridelia ndellensis Stem Bark Extracts - sapub

    : Antidiabetic and Antiplatelet Aggregation Activities of Bridelia ndellensis Stem Bark Extracts 3.2. Lipid Profile of NIDDM Rats after 28 D ays of Treatment with the Ethanol Extract of B. ndellensis Figure 3 shows the serum levels of total cholesterol, triglycerides, HDL cholesterol of normal and experimental diabetic animals.

  • Evaluation of Anti-Platelet Aggregation Effect of Some ...

    Although there are citations of antiplatelet aggregation activity of some Allium species (15-17), there are no previous reports, at least to our knowledge, on the activity of the genus on in-vitro platelet aggregation induced by AA and ADP.

    Published in: Iranian Journal of Pharmaceutical Research 2015Authors: Zahra Lorigooini Seyed Abdolmajid Ayatollahi Salimeh Amidi Farzad KobarfardAffiliation: Shahid Beheshti University of Medical Sciences and Health ServicesAbout: Text mining Bioinformatics
  • Kamuning / Murraya paniculata / orange jessamine ...

    • Antiplatelet Aggregation / Coumarins / Leaves: ... Of the plant parts, the cortex of the root and stem was the most effective. (14) • Hypoglycemic: Study of a hydroalcoholic extract of leaves showed hypoglycemic effects in oxidative stress condition. The mechanism may be through potentiation of insulin effect either by increased ...

  • In vitro antiplatelet activity-guided fractionation of ...

    Apr 26, 2005  To determine the in vitro antiplatelet aggregation property, 100 μl of the various fractions of the plant, in different concentrations (100 μg/ ml, 200 μg/ml, 400 μg/ml, 500 μg/ml), respectively was added to the platelet suspension at different concentrations for 1 min exposure at 37° before treatment with platelet aggregating agents ...

  • ANTICOAGULANTS Pharmacological agents Medicinal Plants

    May 23, 2010  ANTICOAGULANTS are agents that prevent the clotting of blood.Blood coagulation involves the conversion of fluid blood to a solid gel or a clot. The formation of a clot contributes to the process of haemostasis (see HAEMOSTATICS).The formation of fibrin filament, together with the adhesion and activation of platelets, helps form the haemostatic plug, which serves to block the

  • Antiplatelet actions of some coumarin compounds isolated ...

    The phosphoinositide breakdown caused by collagen and PAF was also inhibited by these compounds. They did not affect fibrinogen-induced aggregation of elastase-treated platelets. These antiplatelet actions were immediate, reversible by washout and independent on the

  • Antiplatelet aggregation and antimicrobial activities of ...

    Bael (Aegle marmelos Linn.) has been used in the Indian traditional systems for treating various ailments. In the recent past there have been numerous studies indicating various bioactivities with different parts of the plant. A study has been undertaken to assess the antiplatelet aggregation activities and antimicrobial activities of the Bael.

  • Phytochemical assay and Antiplatelet Activity of Fractions ...

    The secretion of active compounds from three different storage antiplatelet aggregation at 30 ì M concentration of EPN granules (dense granules, a-granules and lysosomes), showed similar activity among aspirin, water fraction and shedding of microvesicles, formation of platelet butanol fraction of velvet bean (Table 2).

  • COMPARATIVE FUNCTION-STRUCTURAL ANALYSIS OF

    Guo et al., J. Anim. Plant Sci. 24(3):2014 926 COMPARATIVE FUNCTION-STRUCTURAL ANALYSIS OF ANTIPLATELET AND ANTIRADICAL ACTIVITIES OF FLAVONOID PHYTOCHEMICALS Chunmei Guo, Shuqing Liu*, Yimeng Guo, Yuling Yin, Jintao Lin, Xin Chen and Ming-Zhong Sun

    Published in: Journal of Animal and Plant Sciences 2014Authors: Guo Chunmei Liu Shuqing Guo Yimeng Yin Yuling Lin Jintao Chen XinAbout: Hesperidin Naringin Quercetin Platelet